Menthol as anesthesic for dourado (Salminus brasiliensis)
Keywords:
alternative anesthetic, Mentha spp., freshwater fish, native speciesAbstract
Different levels of menthol as an anesthetic for dourado (Salminus brasiliensis) were evaluated in this study. Fish (n=32) with average weight of 194.13 ± 9.06 g and total mean length of 25.30 ± 0.90 cm were separated in four groups composed of 8 individuals. Each group was submitted to different menthol concentrations: 60, 90, 120 and 150 mg L-1. Total induction time was analyzed by polynomial regression and other parameters by Tukey´s test. All experimental fish exposed to different concentrations of menthol reached deep anesthesia stage without mortality. It was observed a negative linear effect (P<0.05) for total induction time. The longest recovery time (172.60 s) was observed for dourado treated with 120 mg. L-1, which differed (P<0.05) from the 90 mg.L-1 treatment (122.03 s). All levels evaluated in this study were safe and effective. A concentration of 60 mg L-1 for dourado is suggested based on lower cost and adequate induction and recovery time responses.
References
AOSHIMA, H. e HAMAMOTO, K. 1999 Potentiation of GABAA receptors expressed in
Xenopus oocytes by perfumes and phytoncid.Bioscience, Biotechnology, and Biochemistry,Tokyo, 63: 743í 748.
BRAGA, L.G.T.; BORGHESI, R.; DAIRIKI, J.K.;CYRINO, J.E.P. 2007 Trí¢nsito gastrintestinal
de dieta seca em Salminus brasiliensis. Pesquisa Agropecuária Brasileira, Brasília, 42(1): 131-134.
CHO, G.K. e HEAT, D.D. 2000 Comparison of tricaine methanesulphonate (MS222) and clove oil anaesthesia effects on the physiology of juvenile Chinook salmon Oncorhynchus tshawytscha (Walbaum). Aquaculture Research,Oxford, 31: 537-546.
DUARTE, D.F. 1994 Farmacocinética e farmacodiní¢mica dos anestésicos venosos.
Revista Brasileira de Anestesiologia, Rio de Janeiro, 44(1): 35-42.
FAí"¡ANHA, M.F. e GOMES, L.C. 2005 A eficácia do mentol como anestésico para tambaqui (Colossoma macropomum). Acta Amazonica,Manaus, 35(1): 71-75.
Food and Drug Administration's Center for Veterinary Medicine - FDA/CVM. 2007
Guidance for industry: concerns related to the use of clove oil as an anesthetic for fish. Rockville. 3p. Disponível em:http://www.fda.gov/downloads/AnimalV
eterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/ucm052520.pdf
Acesso em: 14 dez. 2009.
GELAL, A. 2008 Influence of menthol on first pass elimination. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, Santiago,
7(2): 119-124.
GONí"¡ALVES, A.F.N.; SANTOS, E.C.C.;FERNANDES, J.D.K.; TAKAHASHI, L.S. 2008
Mentol e eugenol como substitutos da benzocaína na indução anestésica de juvenis
de pacu. Acta Scientiarum: Animal Sciences,Maringá, 3(3): 339-344.
GUÉNETTE, S.A.; UHLAND, F.C.; HÉLIE, P.;BEAUDRY, F.; VACHON, P. 2007
Pharmacokinetics of eugenol in rainbow trout (Oncorhynchus mykiss). Aquaculture,
Amsterdam, 266(1/4): 262-265.
INOUE, L.A.K.A.; SANTOS-NETO, C.; MORAES,G. 2003 Clove oil as anaesthetic for juveniles of matrinxã Brycon cephalus (Gunther, 1869).Ciência Rural, Santa Maria, 33(5): 943-947.
HISANO, H.; ISHIKAWA, M.M.; FERREIRA, R.A.; BULGARELLI, A.L.A.; COSTA, T.R.;
PÁDUA, S.B. 2008 Tempo de indução e de recuperação de dourados Salminus brasiliensis (Cuvier, 1816), submetidos a diferentes concentrações de óleo de cravo Eugenia sp.Acta Scientiarum: Biological Sciences, Maringá,30(3): 303-307.
LORENZO, D.; PAZ, D.; DELLACASSA, E.;DAVIES, P.; VILA, R.; CAí"˜IGUERAL, S.
2002 Essential oils of Mentha pulegium and Mentha rotundifolia from Uruguay. Brazilian Archives of Biology and Technology, Curutiba,45(4): 519-524.
MUNDAY, P.L. e WILSON, S.K. 1997 Comparative efficacy of clove oil and other
chemicals in anaesthetization of Pomacentrus amboinensis, a coral reef fish. Journal of Fish Biology, London, 51: 931-938.
MYLONAS, C.C.; CARDINALETTI, G.;SIGELAKI, I.; POLZONETTI-MAGNI, A.
2005 Comparative efficacy of clove oil and 2-phenoxyethanol as anesthetics in the
aquaculture of European sea bass(Dicentrarchus labrax) and gilthead sea bream
(Sparus aurata) at different temperatures.Aquaculture, Amsterdam, 246(1/4): 467-481.
NATIONAL CANCER INSTITUTE - NCI. 1979 Bioassay of dl-menthol for possible
carcinogenicity. Bethesda. 126p. (NCI.Technical Report Series, 98).
NATIONAL TOXICOLOGY PROGRAM í NTP. 1983 Toxicology and carcinogenesis
studies of eugenol in F344/N rats and B6C3F1 mice (Feed studies). 420p. (NTP. Technical Report Series, 223).
NATIONAL TOXICOLOGY PROGRAM í NTP.2000 Toxicology and carcinogenesis studies of methyleugenol in F344/N rats and B6C3F1 mice (Gavage studies). 420p. (NTP. Technical Report Series, 491).
NATIONAL TOXICOLOGY PROGRAM - NTP.2008 Toxicology and carcinogenesis studies of isoeugenol (CAS NO. 97-54-1) in F344/N rats and B6C3F1 mice (Gavage studies). 208p. (NTP.Technical Report Series, 551).
PEREIRA-DA-SILVA, E.M.; OLIVEIRA, R.H.F.;RIBEIRO, M.A.R.; COPOLLA, M.P. 2009
Efeito anestésico do óleo de cravo em alevinos de lambari. Ciência Rural, Santa Maria, 39(6):1851-1856.
ROUBACH, R.; GOMES, L.C.; FONSECA, F.A.L.;VAL, A.L. 2005 Eugenol as an efficacious
anaesthetic for tambaqui, Colossoma macropomum (Cuvier). Aquaculture Research,
Oxford, 36(11): 1056-1061.
SIMí-ES, L.N. e GOMES, L.C. 2009 Eficácia do mentol como anestésico para juvenis de
tilápia do nilo. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Belo Horizonte, 61(3):613-620.
SOUZA, I.L.; SANTOS-SILVA, L.K.; VENERE, P.C.; MOREIRA-FILHO, O. 2008 Molecular
cytogenetics of Salminus fish (Characiformes) based on 5S and 18S rRNA genes
hybridization, fluorochrome staining and Cbanding. Micron, New York, 39(7): 1036í 1041.
VIDAL, L.V.O.; FURUYA, W.M.; GRACIANO,T.S.; SCHAMBER, C.R.; SANTOS, L.D.;
MARTINS, C. 2007 Concentrações de eugenol para anestesia profunda e toxidade aguda em juvenis de piavuçú (Leporinus macrocephalus).Acta Scientiarum: Biological Sciences, Maringá,29(4): 357-362.
VIDAL, L.V.O.; ALBINATI, R.C.B.; ALBINATI,A.C.L.; LIRA, A.D.; ALMEIDA, T.R.;
SANTOS, G.B. 2008 Eugenol como anestésico para a tilápia-do-nilo. Pesquisa Agropecuária Brasileira, Brasília, 43(8): 1069-1074.
WATERSTRAT, P.R. 1999 Induction and recovery from anaesthesia in channel catfish Ictalurus punctatus fingerlings exposed to clove oil.Journal of World Aquaculture Society, Baton Rouge, 30(2): 250-255.
WATT, E.E.; BETTS, B.A.; KOTEY, F.O.;HUMBERT, D.J.; GRIFFITH, T.N.; KELLY,
E.W.; VENESKEY, K.C.; GILL, N.; ROWAN, K.C.; JENKINS, A.; HALL, A.C. 2008
Menthol shares general anesthetic activity and sites of action on the GABAA receptor
with the intravenous agent, propofol.European Journal of Pharmacology, Amsterdam, 590(1/3): 120-126.
WEBER, R.A.; PELETEIRO, J.B.; GARCÍA MARTÍN, L.O.; ALDEGUNDE, M. 2009 The
efficacy of 2-phenoxyethanol, metomidate, clove oil and MS-222 as anaesthetic agents in the Senegalese sole (Solea senegalensis Kaup 1858). Aquaculture, Amsterdam, 288(1/2):147-150.
WEINGARTNER, M. e ZANIBONI-FILHO, E.2005 Dourado. In: BALDISSEROTTO, B. e
GOMES, L.C. (Ed.). Espécies nativas para a piscicultura no Brasil. p.257-286.
WOODY, C.A.; NELSON, J.; RAMSTAD, K. 2002 Clove oil as an anesthetic for adult sockeye salmon: field trails. Journal of Fish Biology,London, 60(2): 340-347.
YADEGARINIA, D.; GACHKAR, L.; REZAEI,M.B.; TAGHIZADEH, M.; ASTANEH, S.A.;
RASOOLI, I. 2006 Biochemical activities of Iranian Mentha piperita L. and Myrtus
communis L. essential oils. Phytochemistry,New York, 67(12): 1249-1255.
ZHANG, X-B.; JIANG, P.; GONG, N.; HU, X-L; FEI, D. XIONG, Z-Q; XU, L.; XU, T-L. 2008 Atype GABA receptor as a central target of TRPM8 agonist menthol. Plos One, San
Francisco, 3(10): 1-11.
Xenopus oocytes by perfumes and phytoncid.Bioscience, Biotechnology, and Biochemistry,Tokyo, 63: 743í 748.
BRAGA, L.G.T.; BORGHESI, R.; DAIRIKI, J.K.;CYRINO, J.E.P. 2007 Trí¢nsito gastrintestinal
de dieta seca em Salminus brasiliensis. Pesquisa Agropecuária Brasileira, Brasília, 42(1): 131-134.
CHO, G.K. e HEAT, D.D. 2000 Comparison of tricaine methanesulphonate (MS222) and clove oil anaesthesia effects on the physiology of juvenile Chinook salmon Oncorhynchus tshawytscha (Walbaum). Aquaculture Research,Oxford, 31: 537-546.
DUARTE, D.F. 1994 Farmacocinética e farmacodiní¢mica dos anestésicos venosos.
Revista Brasileira de Anestesiologia, Rio de Janeiro, 44(1): 35-42.
FAí"¡ANHA, M.F. e GOMES, L.C. 2005 A eficácia do mentol como anestésico para tambaqui (Colossoma macropomum). Acta Amazonica,Manaus, 35(1): 71-75.
Food and Drug Administration's Center for Veterinary Medicine - FDA/CVM. 2007
Guidance for industry: concerns related to the use of clove oil as an anesthetic for fish. Rockville. 3p. Disponível em:http://www.fda.gov/downloads/AnimalV
eterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/ucm052520.pdf
Acesso em: 14 dez. 2009.
GELAL, A. 2008 Influence of menthol on first pass elimination. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, Santiago,
7(2): 119-124.
GONí"¡ALVES, A.F.N.; SANTOS, E.C.C.;FERNANDES, J.D.K.; TAKAHASHI, L.S. 2008
Mentol e eugenol como substitutos da benzocaína na indução anestésica de juvenis
de pacu. Acta Scientiarum: Animal Sciences,Maringá, 3(3): 339-344.
GUÉNETTE, S.A.; UHLAND, F.C.; HÉLIE, P.;BEAUDRY, F.; VACHON, P. 2007
Pharmacokinetics of eugenol in rainbow trout (Oncorhynchus mykiss). Aquaculture,
Amsterdam, 266(1/4): 262-265.
INOUE, L.A.K.A.; SANTOS-NETO, C.; MORAES,G. 2003 Clove oil as anaesthetic for juveniles of matrinxã Brycon cephalus (Gunther, 1869).Ciência Rural, Santa Maria, 33(5): 943-947.
HISANO, H.; ISHIKAWA, M.M.; FERREIRA, R.A.; BULGARELLI, A.L.A.; COSTA, T.R.;
PÁDUA, S.B. 2008 Tempo de indução e de recuperação de dourados Salminus brasiliensis (Cuvier, 1816), submetidos a diferentes concentrações de óleo de cravo Eugenia sp.Acta Scientiarum: Biological Sciences, Maringá,30(3): 303-307.
LORENZO, D.; PAZ, D.; DELLACASSA, E.;DAVIES, P.; VILA, R.; CAí"˜IGUERAL, S.
2002 Essential oils of Mentha pulegium and Mentha rotundifolia from Uruguay. Brazilian Archives of Biology and Technology, Curutiba,45(4): 519-524.
MUNDAY, P.L. e WILSON, S.K. 1997 Comparative efficacy of clove oil and other
chemicals in anaesthetization of Pomacentrus amboinensis, a coral reef fish. Journal of Fish Biology, London, 51: 931-938.
MYLONAS, C.C.; CARDINALETTI, G.;SIGELAKI, I.; POLZONETTI-MAGNI, A.
2005 Comparative efficacy of clove oil and 2-phenoxyethanol as anesthetics in the
aquaculture of European sea bass(Dicentrarchus labrax) and gilthead sea bream
(Sparus aurata) at different temperatures.Aquaculture, Amsterdam, 246(1/4): 467-481.
NATIONAL CANCER INSTITUTE - NCI. 1979 Bioassay of dl-menthol for possible
carcinogenicity. Bethesda. 126p. (NCI.Technical Report Series, 98).
NATIONAL TOXICOLOGY PROGRAM í NTP. 1983 Toxicology and carcinogenesis
studies of eugenol in F344/N rats and B6C3F1 mice (Feed studies). 420p. (NTP. Technical Report Series, 223).
NATIONAL TOXICOLOGY PROGRAM í NTP.2000 Toxicology and carcinogenesis studies of methyleugenol in F344/N rats and B6C3F1 mice (Gavage studies). 420p. (NTP. Technical Report Series, 491).
NATIONAL TOXICOLOGY PROGRAM - NTP.2008 Toxicology and carcinogenesis studies of isoeugenol (CAS NO. 97-54-1) in F344/N rats and B6C3F1 mice (Gavage studies). 208p. (NTP.Technical Report Series, 551).
PEREIRA-DA-SILVA, E.M.; OLIVEIRA, R.H.F.;RIBEIRO, M.A.R.; COPOLLA, M.P. 2009
Efeito anestésico do óleo de cravo em alevinos de lambari. Ciência Rural, Santa Maria, 39(6):1851-1856.
ROUBACH, R.; GOMES, L.C.; FONSECA, F.A.L.;VAL, A.L. 2005 Eugenol as an efficacious
anaesthetic for tambaqui, Colossoma macropomum (Cuvier). Aquaculture Research,
Oxford, 36(11): 1056-1061.
SIMí-ES, L.N. e GOMES, L.C. 2009 Eficácia do mentol como anestésico para juvenis de
tilápia do nilo. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Belo Horizonte, 61(3):613-620.
SOUZA, I.L.; SANTOS-SILVA, L.K.; VENERE, P.C.; MOREIRA-FILHO, O. 2008 Molecular
cytogenetics of Salminus fish (Characiformes) based on 5S and 18S rRNA genes
hybridization, fluorochrome staining and Cbanding. Micron, New York, 39(7): 1036í 1041.
VIDAL, L.V.O.; FURUYA, W.M.; GRACIANO,T.S.; SCHAMBER, C.R.; SANTOS, L.D.;
MARTINS, C. 2007 Concentrações de eugenol para anestesia profunda e toxidade aguda em juvenis de piavuçú (Leporinus macrocephalus).Acta Scientiarum: Biological Sciences, Maringá,29(4): 357-362.
VIDAL, L.V.O.; ALBINATI, R.C.B.; ALBINATI,A.C.L.; LIRA, A.D.; ALMEIDA, T.R.;
SANTOS, G.B. 2008 Eugenol como anestésico para a tilápia-do-nilo. Pesquisa Agropecuária Brasileira, Brasília, 43(8): 1069-1074.
WATERSTRAT, P.R. 1999 Induction and recovery from anaesthesia in channel catfish Ictalurus punctatus fingerlings exposed to clove oil.Journal of World Aquaculture Society, Baton Rouge, 30(2): 250-255.
WATT, E.E.; BETTS, B.A.; KOTEY, F.O.;HUMBERT, D.J.; GRIFFITH, T.N.; KELLY,
E.W.; VENESKEY, K.C.; GILL, N.; ROWAN, K.C.; JENKINS, A.; HALL, A.C. 2008
Menthol shares general anesthetic activity and sites of action on the GABAA receptor
with the intravenous agent, propofol.European Journal of Pharmacology, Amsterdam, 590(1/3): 120-126.
WEBER, R.A.; PELETEIRO, J.B.; GARCÍA MARTÍN, L.O.; ALDEGUNDE, M. 2009 The
efficacy of 2-phenoxyethanol, metomidate, clove oil and MS-222 as anaesthetic agents in the Senegalese sole (Solea senegalensis Kaup 1858). Aquaculture, Amsterdam, 288(1/2):147-150.
WEINGARTNER, M. e ZANIBONI-FILHO, E.2005 Dourado. In: BALDISSEROTTO, B. e
GOMES, L.C. (Ed.). Espécies nativas para a piscicultura no Brasil. p.257-286.
WOODY, C.A.; NELSON, J.; RAMSTAD, K. 2002 Clove oil as an anesthetic for adult sockeye salmon: field trails. Journal of Fish Biology,London, 60(2): 340-347.
YADEGARINIA, D.; GACHKAR, L.; REZAEI,M.B.; TAGHIZADEH, M.; ASTANEH, S.A.;
RASOOLI, I. 2006 Biochemical activities of Iranian Mentha piperita L. and Myrtus
communis L. essential oils. Phytochemistry,New York, 67(12): 1249-1255.
ZHANG, X-B.; JIANG, P.; GONG, N.; HU, X-L; FEI, D. XIONG, Z-Q; XU, L.; XU, T-L. 2008 Atype GABA receptor as a central target of TRPM8 agonist menthol. Plos One, San
Francisco, 3(10): 1-11.
Downloads
Published
2018-11-08
Issue
Section
Short Communication
